Underestimation of the Calculated Area Under the Concentration-Time Curve Based on Serum Creatinine for Vancomycin Dosing
نویسندگان
چکیده
منابع مشابه
Underestimation of the Calculated Area Under the Concentration-Time Curve Based on Serum Creatinine for Vancomycin Dosing
BACKGROUND The ratio of the steady-state 24-hour area under the concentration-time curve (ssAUC24) to the MIC (AUC24/MIC) for vancomycin has been recommended as the preferred pharmacodynamic index. The aim of this study was to assess whether the calculated AUC24 (cAUC24) using the creatinine clearance (CLcr) differs from the ssAUC24 based on the individual pharmacokinetic data estimated by a co...
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ژورنال
عنوان ژورنال: Infection & Chemotherapy
سال: 2014
ISSN: 2093-2340,2092-6448
DOI: 10.3947/ic.2014.46.1.21